COMPUTER-BASED PREDICTION OF TOXICITY USING THE ELECTRON-CONFORMATIONAL METHOD. APPLICATION TO FRAGRANCE ALLERGENS AND OTHER ENVIRONMENTAL POLLUTANTS

The electron-conformational (EC) method is employed for the toxicophore (Tph) identification and quantitative prediction of toxicity using the training set of 24 compounds that are considered as fragrance allergens.The values of a=LD50 in oral exposure of rats were chosen as a measure of toxicity.EC parameters are evaluated on the base of conformat

Antibiotics have been used to maintain the overall health of poultry by increasing production efficiency, promoting growth, and improving intestinal function for more than 50 years.However, they have a number of side effects, such as antibiotic resistance, gut dysbiosis, destruction of beneficial bacteria, and the potential to spread diseases to hu

Dystrophic epidermolysis bullosa (DEB) is a hereditary mechanobullous welding sweater disorder characterized by fragility of the skin and mucous membranes caused by abnormal anchoring fibrils.Both dominant and recessive DEB are caused by mutations in COL7A1, the gene encoding type VII collagen, the major component of anchoring fibrils.We performed

Schizophrenia patient who withdraws from others and reality often comes into life of fantasy that is full delusion and hallucination.In process of experiencing the disease, patient schizophrenia often relapse after completed treatment either g35 coupe fender in hospital medical therapy or non medical therapy.This study attempted to know the caution

In this paper we present a case study of a record low ozone event observed over the UK in January 2006.We focus on the dynamical processes that cause this event.This is done by examining the observations, meteorological analyses and back trajectories calculated by the NAME III atmospheric dispersion model.We show that this model, hitherto only used